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Frank Pruett
Frank Pruett

Cyane Lima


Research on experimental animals confirmed the anti-inflammatory and anti-nociceptive effects of the synthetic compound α and β epoxy carvone (da Rocha et al., 2013da Rocha ML, Oliveira LE, Patricio Santos CC, de Sousa DP, de Almeida RN, Araujo DA. Anti-nociceptive and anti-inflammatory effects of the monoterpene α, β-epoxy-Carvone in mice. J Nat Med. 2013;67(4):743-9.) and cyane-carvone (Marques et al., 2014Marques TH, Marques ML, Medeiros JV, Silva RO, dos Reis Barbosa AL, Lima TC, de Sousa DP, de Freitas RM. Cyane-Carvone, a synthetic derivative of carvone, inhibits inflammatory response by reducing cytokine production and oxidative stress and shows anti-nociceptive effect in mice. Inflammation. 2014;37(3):966-77.). Carvone decreases the formation of inflammatory cytokines and it also has a role in oxidative stress mechanisms. The anti-inflammatory effects of carvone in carrageenan induced edema and the measurement of Myeloperoxidase showed that the most important cytokines having a role in inflammatory mechanisms are IL-β1 and TNFα (Marques et al., 2014Marques TH, Marques ML, Medeiros JV, Silva RO, dos Reis Barbosa AL, Lima TC, de Sousa DP, de Freitas RM. Cyane-Carvone, a synthetic derivative of carvone, inhibits inflammatory response by reducing cytokine production and oxidative stress and shows anti-nociceptive effect in mice. Inflammation. 2014;37(3):966-77.).




cyane lima

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